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Investigation Protocols

Written by Craig Webster on .

Protocols can be downloaded from here

Pathology Phone Limits

Written by Craig Webster on .

Phoning limits for biochemistry tests are as follows:

  Below Above Units
Sodium 120 150 mmol/L
Potassium 3 6.5 mmol/L
Urea   30 mmol/L
Creatinine   500 umol/L
Glucose 2.5 20 mmol/L
Calcium adjusted 1.8 3.5 mmol/L
Magnesium 0.4   mmol/L
Phosphate 0.3   mmol/L
AST   700 U/L
ALT   400 U/L
Total CK   500 U/L
Amylase   600 U/L
TBA   20 umol/L
Iron   70 umol/L
Total bilirubin   225 umol/L
Carbamazepine   25 ug /mL
Digoxin   2.5 ng/mL
Theophylline   45 mg/L
Phenytoin   20 mg/L
Phenobarbitone   70 mg/L
Lithium  <0.2 >1.5 mmol/L
Valproate   100 mg/L
Cyclosporin A   200 ug/L
CRP  

300

phoned with other abnormal results

mg/L
Salicylate   20 mg/L
Paracetamol   10 mg/L
Ammonia All phoned    
Lactate All phoned    
beta-HCG All phoned    
progesterone All phoned    
CSF glucose All phoned    
CSF protein All phoned    
NNU results All phoned    

 

PREDNISOLONE METABOLISM TEST

Written by Craig Webster on .

PREDNISOLONE METABOLISM TEST

Aim: 

To assess prednisolone metabolism in steroid dependent asthmatics

Justification:

Small group of asthmatics remain symptomatic despite long term treatment with oral corticosteroids “prednisolone”, with major implication in terms of steroid induced side effects.  The cause of this lack of effect could be due to poor adherence, malabsorption, rapid metabolism or genetically mediated resistance to steroids.  The aim of this test is to assess the cause of the apparent lack of responsiveness to steroids in a patient.