Haemoglobin A1c and the diagnosis of diabetes mellitus

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Conventionally diabetes mellitus has been diagnosed by high fasting or random blood glucose concentrations, or abnormal oral glucose tolerance tests (OGTT). Haemoglobin A1c (HbA1c) has been used to monitor longer term glycaemic control in patients with known diabetes mellitus.

Key Factors That can Affect Results

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Common causes of spurious results due to incorrect collection or storage

Note: Common analytical interferences are screened for and if detected no results will be reported for that analyte.

Sample transport by Airtube (Exceptions)

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 The following sample types should not be sent via the airtube system

  • CSF for Xanthochromia analysis
  • Pleural fluids for any analysis 

Opening Hours: 24 Hour Service

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The Department operates a 24 hr service, 7 days a week. 

To ensure that immediate attention is given to emergency requests, doctors must phone the laboratory to ensure that staff are aware of the priority. It is the responsibility of the requesting doctor to ensure the sample is sent to the Department.

For out of hours clinical advice (17:30 - 09:00), please contact switchboard and ask for the Duty Consultant Biochemist on-call. Consultant advice for immunology is also available via switchboard

 

Emergency Tests (Biochemistry)

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IT SHOULD BE REMEMBERED THAT AN EMERGENCY REQUEST SHOULD NOT BE MADE UNLESS THE RESULT IS REQUIRED FOR THE IMMEDIATE MANAGEMENT OF THE PATIENT.

An emergency service is provided for the following tests

All routine biochemistry including digoxin and osmolality (excluding cyclosporin and xanthochromia analysis)

Biochemical Profiles

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Liver function

Protein, Albumin, Bilirubin, ALT, ALP with GGT automatically reflex tested if ALP > 200

Renal/Electrolytes

Sodium, Potassium, Urea, Creatinine