Department

Referred Work
C3D

Preferred Sample Type

C3d LEVELS, C3 BREAKDOWN PRODUCT

Suitable Specimen Types

  • EDTA Plasma
2 mL

Specimen Transport

1st class post overnight to referral laboratory ( frozen sample) transport on dry ice not required

Sample Processing in Laboratory

Separate within 60 minutes of venepuncture and freeze

Turnaround Time

4 weeks

Sample Stability

Seperate within 60 minutes of venepuncture and freeze prior to overnight transport to referral laboratory

C3d LEVELS, C3 BREAKDOWN PRODUCT

General Information

C3d is a useful marker of complement consumption as it is not affected by the acute phase response, unlike C3 which may remain within the normal range despite significant consumption. This test may be clinical useful to determine whether low complement levels indicate active consumption or deficiency. Determining complement consumption can also be used to monitor disease activity in conditions such as SLE Rhematoid arthritis

Notes

Serum samples may give falsely elevated levels of C3d, EDTA plasma must be used.

Reference Range

Normal values <5 mg/L.

Source of Reference Range

Reference range established in house.at referral laboratory

Specifications

  • EQA Scheme?: No
  • EQA Status: No EQA scheme currently available.

Link to Further Information

http://www.immqas.org.uk/TestItem.asp?id=155

Link to Send Away Laboratory

http://www.immqas.org.uk/pru.asp

Date Record Created

Thursday, 20 December 2018

Date last updated

Thursday, 20 December 2018

Review Date

Monday, 30 November -0001

Location of Laboratories

Patient Information

General Information

The laboratories at Heartlands Hospital, Good Hope Hospital and Solihull Hospital form part of the services provided by University Hospitals Birmingham and are UKAS (United Kingdom Accreditation Service) accredited to the ISO 15189:2012 standard. For a list of accredited tests and other information please visit the UKAS website using the following link: https://www.ukas.com/find-an-organisation/

  • Heartlands, Good Hope and Solihull Hospital pathology laboratories are a UKAS accredited medical laboratory No.8217
  • United Kingdom Health Security Agency laboratory is a UKAS accredited medical laboratory No.8213

Tests not appearing on the UKAS Schedule of Accreditation currently remain outside of our scope of accreditation. However, these tests have been validated to the same high standard as accredited tests and are performed by the same trained and competent staff.

For further test information, please visit the test database: https://heftpathology.site/frontpage/test-database.html.

Protection of personal information - Laboratory Medicine comply with the Trust Data Protection policy and have procedures in place to allow the Directorate and its employees to comply with the Data Protection act  1998 and associated best practice and guidance.

For further information contact Louise Fallon, Quality Manager, 0121 424 1235

UKAS HEFT